The Norwegian ELIXIR node is divided into five subnodes.
Head: Inge Jonassen.
The Bergen node is organized at the Computational Biology Unit (CBU), University of Bergen (UiB). We provide broad services of bioinformatics, mainly on high-throughput omics data analysis. That includes high-throughput sequencing data (i.e. Exome-seq, RNA-seq and ChIP-seq), gene expression microarrays and quantitative proteomics datasets. We also provide consulting on planning and design of high-throughput technology based experiments. The biological topics in focus are based on our collaborators’ research areas and these include medical research at Haukeland University Hospital, Bergen, and marine biology at the Department of Biology, UiB and the Marine Research Institute (IMR). Furthermore we develop bioinformatics analysis infrastructure including e.g. Galaxy workflows, as part of the Norwegian e-infrastructure for Life Science (NeLS).
Head: Eivind Hovig
The Oslo Bioinformatics Core Facility provides its users at the Oslo University Hospital and the University of Oslo with a range of services within bioinformatics, including analysis of high-throughput sequencing data, microarray data, protein structure analysis, statistical genomics and access to useful databases and web services. Besides the service activity we are participating in the development and maintenance of the Genomic HyperBrowser.
Head: Nils Peder Willassen
The historical and geographical position has made it natural for the UiT The Arctic University of Norway to focus on life in the marine environment. The last decade, much attention has been given to marine genomics and bioprospecting and the potential to find biocatalysts with novel functions that may be of therapeutically or biotechnological interest. The scientists associated with the platform in Tromsø mainly have experience from working with prokaryotic organisms from the arctic oceans. Research topics related to metagenome analysis, prokaryotic genomics and transcriptomics can be addressed here. The Tromsø node has developed tools to analyze high-throughput data for this type of projects. The node has also developed computational and visualization tools for analysis and interactive exploration of data from a large-scale cancer postgenome biobank (NOWAC).
Head: Finn Drabløs
The platform activity at NTNU is co-localized with the Bioinformatics Core Facility (BioCore). The associated research group is mainly working on gene regulation, large-scale genomics towards cancer research and population biobanks (HUNT), and prokaryote genomics. Our collaborators include the biomedical and the biotech community, as well as private industry. The group develops tools for microRNA target prediction, non-coding RNA gene prediction, analysis of regulatory regions, peak finding in ChIP-seq data for transcription factors, and integrated handling and analysis of genomic data in biobanks. The platform also develops and implements specific pipelines for analysing sequencing data, e.g. from RNA-sequencing, micro-RNA or other non-coding RNA experiments, and analysis of exome sequencing or whole genome sequencing data. The Trondheim node also has competence on sequencing data from prokaryotic genomes and metagenomic sequencing data.
Head: Dag Inge Våge
The ELIXIR node at Ås is part of Centre for Integrative Genetics (CIGENE), Department of Animal and Aquacultural Sciences at NMBU. We are an active partner in both the International Cooperation to Sequence the Atlantic Salmon Genome (ICSASG) and the national AquaGenome-project. The Ås node will make fish genomic resources available to the ELIXIR-network, with a particular focus on the salmon genome. Web based solutions and e-infrastructure for analysing and sharing species-specific and comparative genomics resources are currently under development.